- 作 者：吴达俊，庄思永主编
- 出 版 社：北京：化学工业出版社
- 出版年份：2000
- ISBN：7502528040
- 注意：在使用云解压之前，请认真核对实际PDF页数与内容!
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PART 1 MEDICINAL CHEMISTRY 1
Unit 1 Production of Drugs 1
Reading Material 1 Past Approaches to Discovering New Drugs as Medicines 7
Unit 2 Structural Features and Pharmacologic Activity (Ⅰ) 15
Reading Material 2 Structural Features and Pharmacologic Activity (Ⅱ) 23
Unit 3 Chemotherapy: An Introduction(Ⅰ) 29
Reading Material 3 Chemotherapy:an Introduction (Ⅱ) 35
Unit 4 Novel Analgesics 42
Reading Material 4 Mild Analgesics-Antipyretics 49
Unit 5 Drug Development (Ⅰ) 54
Reading Material 5 Drug Development (Ⅱ) 61
PART 2 BIOCHEMICAL PHARMACEUTICALS 67
Unit 6 Isolation of Caffeine from Tea 67
Reading Material 6 Medicinal of Plant Origin:Historical Aspects 71
Unit 7 Developing Drugs from Traditional Medicinal Plants 76
Reading Material 7 Naturally Occurring Flavans Unsubstituted in the Heterocyclic Ring 82
Unit 8 The Chemistry of Insulin 86
Reading Material 8 Steroid Saponins 91
Unit 9 Multidrug-Resistant Bacterial Infections:Driving the Search for New Antibiotics 96
Reading Material 9 Beta-Lactams Past and Present 101
Unit 10 Preparation and Purification of Heparin 107
Reading Material 10 Deoxyribonucleic Acid 113
PART 3 INDUSTRIAL PHARMACY 117
Unit 11 Tablets(The Pharmaceutical Tablets Dosage Form) 117
Reading Material 11 Evaluation 120
Unit 12 Manufacture of Tablets 124
Reading Material 12 Solids Mixing and Drying 127
Unit 13 Sterile Products 131
Reading Material 13 Processing 135
Unit 14 Sustained Release Dosage Forms 139
Reading Material 14 Tableted Slow Release Granulations 143
Unit 15 Kinetic Principles and Stability Testing 146
Reading Material 15 Degradative Pathways 150
PART 4 PHARMACEUTICAL ENGINEERING 152
Unit 16 Reactor Technology 152
Reading Material 16 Fermentation 159
Unit 17 Distillation 164
Reading Material 17 Supercritical Fluid Extraction 170
Unit 18 Crystalization 176
Reading Material 18 Drying 181
Unit 19 Water and Air in the Chemical Process Industries 187
Reading Material 19 Chemical Process Industries and Environmental Pollution Abatement 192
Unit 20 Practical Process Engineering 198
Reading Material 20 Valves 203
Unit 21 Chiral Technology and Single-isomers 210
PART 5 FRONTIERS OF PHARMACEUTICAL ENGINEERING 210
Reading Material 21 When Drug Molecules Look in the Mirror 213
Unit 22 Interferon 217
Reading Material 22 Molecular Recognition:Chemical and Biochemical Problems 220
Unit 23 The Marine Drug Potential 223
Reading Material 23 Drugs from the Sea 226
Unit 24 Catalytic Antibodies Generation of Novel Biocatalysts 230
Reading Material 24 Enzymes in Synthetic Organic Chemistry 233
Unit 25 Principles of Drug Design 236
Reading Material 25 On Computer-Aided Drug Design 239
APPENDIXES 241
Appendix 1 The General Principles for Nomenclature of Chinese Approved Drug Names 241
Appendix 2 INN采用的词干及其中文译名 244
Appendix 3 英汉对照新药名选编 247
总词汇表 256